OPTIMISING A PERSON-CENTRED APPROACH TO STOPPING MEDICINES IN OLDER PEOPLE WITH MULTIMORBIDITY AND POLYPHARMACY USING THE DEXTRUS FRAMEWORK: A REALIST REVIEW

Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review

Abstract Background Tackling problematic polypharmacy requires tailoring the use of medicines to individual circumstances and may involve the process of deprescribing.Deprescribing can cause anxiety and concern for clinicians and patients.Tailoring medication decisions often entails beyond protocol decision-making, a complex process involving emoti

read more

Enhancing Dental Pulp Stem Cell Proliferation and Odontogenic Differentiation with Protein Phosphatase 1-Disrupting Peptide: An In Vitro Study

The reparative and regenerative capabilities of dental pulp stem cells (DPSCs) are crucial for responding to pulp injuries, with protein phosphatase 1 (PP1) playing a significant role in regulating cellular functions pertinent to tissue healing.Accordingly, this study aimed to explore the effects of a novel cell-penetrating peptide Modified Sperm S

read more



Molecular cloning and expression of key gene encoding hypothetical DNA polymerase from B. mori parvo-like virus

BmPLV-Z is the abbreviation for Bombyx mori parvo-like virus (China isolate).This is a novel virus with two single-stranded linear DNA molecules, viz., VD1 (6543 bp) and VD2 (6022 bp), which are encapsidated respectively into 7-OH separate virions.Analysis of the deduced amino acid sequence of VD1-ORF4 indicated the existence of a putative DNA-poly

read more